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This binding switches 15LO1s preferred substrate from free arachidonic acid to arachidonic acid conjugated to PE, which generates ferroptotic lipids, including the hydroperoxy-phospholipid 15-hydroperoxy-eicosatetraenoic acidPE (15-HpETE-PE) (6, 7, 10, 13)

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Taking certain medications may also inhibit B12 absorption in seniors

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3.2.1 Clinical studies A self-experimented clinical study was conducted in individuals diagnosed with Parkinsons disease using broccoli seed tea (2545 mol SF/day for at least 4 weeks, with weekly administration in the first week and up to twice per week thereafter) rich in SF intended to induce Nrf2 (81)