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[The Working Group noted that the study limitations included difficulties in the interpretation of the results on the basis of the pictures provided, lack of criteria on aberration, or inappropriately included gaps.] Chromosomal aberrations were induced in the bone marrow of male albino rats exposed to aspartame at 250 mg/kg bw per day by oral gavage for 90 days (Elballat and Abas, 2020)

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Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells