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Concordant with this hypothesis, we observed that IFN- was important in SerpinB2 reduction in obesity, and the anti-apoptotic role of SerpinB2 has been demonstrated in inflammatory disease pathologies 137,138,139,140,141,142,143,144,145,146

S.Di BisceglieA

Nat Med 2013

Repeated IV/IM doses indeed suggested efficacy for DFO in Alzheimers disease, but such invasive regimens are not practical long-term and carry significant risks

This reduces the nerves capacity to transmit signals detected and collected by sensory nerves to the central nervous system, causing autonomic imbalance and disrupting adipose tissue homeostasis