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Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles

So far, studies on intracellular steroid receptor levels following NO-treatment are sparse

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In different PH models, not only NLRP3 complex was widely observed in the inflammatory cells around the pulmonary vessels [119, 123], but also NLRP3, ASC, and Caspase-1 proteins were abnormally upregulated in PAECs and PASMCs [124, 125]