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Impaired peroxisomal function leads to PUFA accumulation, enhancing lipid peroxidation and ferroptotic cell death

thus, preventing any interaction with the packed human genetic materials [4]

This work was supported by the National Natural Science Foundation of China (82370364, 82274071, 82300414, and 82170424), Jiangsu Province Excellent Youth Foundation (BK20240204), Jiangsu Natural Science Foundation (BK20231049, BE2020634 and BK20191138), Joint research project of the Chinese Society of Traditional Chinese Medicine, high-level introduction of talents and scientific research start-up funds of JNU (1286010241222100), the Fundamental Research Funds for the Central Universities (JUSRP124036), Medical Discipline Program of Wuxi Health Commission, the Science and Technology Projects of Wuxi City (M202207, BJ2023029), Clinical Research and Translational Medicine Research Program of Affiliated Hospital of Jiangnan University (LCYJ202306, LCYJ202226), Wuxi Science and Technology Development Fund Project Light of the Taihu Lake (K20221028), Wuxi Municipal Health Commission Youth Project (Q202226), Top Talent Support Program for young and middle-aged people of Wuxi Health Committee (HB2023045, BJ2023045, BJ2023029)

Virtual Screening, ADMET Prediction, Molecular Docking, and Dynamic Simulation Studies of Natural Products as BACE1 Inhibitors for the Management of Alzheimer's Disease. Scientific Reports 14: 26431

Figure 1 2.2 Generations of CAR-T cells Five generations of CAR-T cells have been developed