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(2018) 13:e0196716

In intestinal epithelial cells, this enhanced contractile tension induces centripetal contraction of the perijunctional actomyosin ring, leading to internalization and reorganization of junctional proteins, including claudins, occludin, ZO-1, and adherens junction components, resulting in reversible TJ opening and increased paracellular permeability

GABBR2 expression levels remained unchanged, confirming the specificity of GABBR1 overexpression ( Figure S4C )

phosphorylated GSK3 (Ser9) level was significantly downregulated in Prx II-knockdown HaCaT cells after H 2 O 2 treatment, accompanied by a marked decrease in the phosphorylation levels of its upstream kinase PI3K and AKT (Fig

Dehydroascorbate reductase consumes reduced glutathione to produce ascorbate, which is then used for the detoxification of hydrogen peroxide