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These findings suggest that high copper levels can exacerbate inflammation of the vascular walls and thus promote atherosclerosis development

Oxygen vacancy-engineered cerium oxide mediated by copper-platinum exhibit enhanced SOD/CAT-mimicking activities to regulate the microenvironment for osteoarthritis therapy

Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)

Mechanistic Research Characteristics Modulation of intracellular signalling pathways in controlled in-vitro systems Influence on growth factor sensitivity and molecular activation cascades Regulation of gene expression patterns in peptide-based research models Interaction with mitochondrial ATP dynamics and metabolic pathways Support of enzymatic response analysis and pathway-driven research designs Primary Research Applications Synergistic Peptide Interaction Studies: Evaluating interaction effects and signal modulation between multiple peptide pathways

Significantly upregulated mRNA expression of AKR1B1 (2.64-fold