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Exogenous ROS is mainly caused by radiation and other conditions, while endogenous ROS is mainly produced by mitochondria and endoplasmic reticulum 57,58

Often, iron chewable tablets are combined with vitamins to improve absorption and taste

Cancer Res (2008) 68:43406

To determine whether the macrophage-derived EVs possessed the capacity to sequester and remove iron, EVs were incubated with different samples including myocardium lysate, cardiomyocytes lysate, serum and cardiomyocyte culture medium (Fig