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p(NIPAAm-co-PAA) (83 mol% NIPAAm, 17 mol% PAA, 37 kDa) copolymers produced hydrogels that released encapsulated VEGF via diffusion over ~7 days at pH 7.4 and over ~3 weeks when pH was lowered to 5 or 6, pH levels consistent with ischemic tissue microenvironments (Garbern et al., in vivo to infarcted myocardium over ~7 days, and improved fractional shortening of and blood flow to the heart, as well as capillary and arteriolar densities as compared to controls (Murry et al., Hybrid materials Combinations of natural and synthetic polymers have also been used to form hybrid hydrogels for controlled drug delivery

Also, the reduced NADH and NADPH forms are volatile in the LC-MS setting due to composition of the mobile phase, making their detection by LC-MS complicated

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The activity of superoxide dismutase enzyme involved in defense of parasite infection is reduced in fish treated with an immunosuppressant (112)

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