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Description

Science (2005) 309:182933

Pretsch G, Sanadgol N, Smidak R, Lubec J, Korz V, Hger H

Author contributions WZ: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing original draft

Trigger shapes AGOmiRNA for E3 binding The substrate-binding regions emanating from the ZSWIM8 dimeric E3 superdomain form a clamp that engulfs the AGO2miR-7CYRANO complex

targeted EC cells with miR-302a overexpressing EXOs, which inhibited their division and migration by lowering cyclin D1 levels and deactivating the AKT signaling (Li et al., 2019)