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Am J Physiol Lung Cell Mol Physiol 283: 766-776

Skin lightening: It works by inhibiting tyrosinase, an enzyme responsible for melanin production, helping to lighten skin tone and reduce the appearance of dark spots

doi: 10.1136/jitc-2022-005871 284 MarquesRFMorenoDAda SilvaLLealLFde PaulaFESantanaIet al

Quercetin (Sigma-Aldrich, USA) was dissolved in DMSO to prepare a stock solution

Because one assumes that water is ubiquitous one does not need to account for protons except for knowing the prevailing pH which depicts the tendency to give or receive protons