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Also, p-cresol is a uremic toxin, found to accumulate in the serum of chronic kidney disease patients [190], revealing deleterious effects on the endothelium in vitro [191, 192], and inducing the formation of EMVs in cultured ECs [193, 194]

Biochim Biophys Acta 1842(3):352357 Meruvu S, Hugendubler L, Mueller E (2011) Regulation of adipocyte differentiation by the zinc finger protein ZNF638