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doi:10.1177/0748233709348393 Islam, M.T., Mishra, S.K., Tripathi, S., de Alencar, M.V.O.B., e Sousa, J.M.d.C., Rolim, H.M.L., de Medeiros, M.d.G.F., Ferreira, P.M.P., Rouf, R., Uddin, S.J., Mubarak, M.S

The preclinical ADC 84-EBET demonstrated complete tumor regression in CRC PDX models

Serum levels of TAC, MDA, MMP2, MMP9, glutathione, and hs-CRP were measured

Then, ribosomes were pelleted through a 1 M sucrose cushion in HS Buffer (20 mM HEPES/KOH pH 7.5, 500 mM KOAc, 2 mM MgCl 2 , 1 mM DTT) in a Type 70 Ti rotor (Beckman Coulter) at 106,700 x g for 18.5 h