glutathione and sjogren's Frontiers Lipid Metabolism: An Emerging Player

This disorder is suspected in patients with hemolytic anemia and markedly reduced red blood cell GSH content

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Their ability to target multiple pathwaysfrom initiating apoptosis and detoxifying carcinogens to reprogramming epigenetics and the tumor microenvironmentpositions ITCs as attractive candidates for integrative oncology approaches (113)

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In cancer cells, crotamine produces a rapid increase of the intracellular Ca 2+ from the endoplasmic reticulum (ER) and lysosomes, m depolarization, and in vivo , it induces selective penetration in proliferating cancer cells and consequently, apoptosis without toxic effect on non-tumoral tissues (48)