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Without adequate selenium, glutathione can't efficiently neutralize peroxides

doi: 10.1136/bmj.c2519 254 TalaulikarVSArulkumaranS

24-28 Clinical features of NA include: Decreased nitric oxide levels 23 Lower blood eosinophil and basophil counts 23 Compromised lung function 23 Chronic neutrophilia 23 Increased need for high-dose inhaled corticosteroids 23 Higher risks of asthma exacerbations 29 Oral corticosteroid dependence in some cases 29 For definitive diagnosis of NA, the gold standard approach combines bronchial biopsy with sputum inflammatory cell analysis

Nature 544 , 367371 (2017)

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