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Dysregulation of these pathways leads to impaired immune responses and increased susceptibility to age-related diseases

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Furthermore, the reduction of Firmicute s and Actinobacteria suggested to the researchers that the high concentrations of ammonia can interfere with nutrient absorption and disrupt intestinal barrier functions which could impact the hosts defense capacity against pathogen invasion

data ( i, j ) pooled from two independent experiments (n = 7/group)