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These findings suggest that increased AKT1 expression is driven by stable epigenetic changes, rather than somatic mutations, underscoring its potential as a modifiable molecular target

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Ristow M, Zarse K, Oberbach A, Klting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Blher M

Insights into the mechanism of SetCys-mediated ligation Having scrutinized the mechanism of SetCys conversion to a Cys residue under strong reductive conditions, we next examined the species involved during ligation with a peptide alkyl thioester under the same redox conditions

[DOI] [PubMed] [Google Scholar] 64.Tsujita N., Akamatsu Y., Nishida M.M., Hayashi T., Moritani T