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Cellular thermal shift assay (CETSA) - western blot (WB) The Cellular Thermal Shift Assay (CETSA) capitalizes on this principle of thermal denaturation to study protein stability and interactions [49,50,51]

However, tumor cells lack catalase, leaving them vulnerable to the cytotoxic effects of hydrogen peroxide (Chen 2005)

This model effectively mimics the symptoms of neuropathic pain experienced by humans, such as allodynia and hyperalgesia, which are caused by peripheral nerve damage and inflammation

Figure 1 The oncogene c-Myc is a major regulator of glutamine utilization in tumor cells (45)

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