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202 In isolated mouse airway epithelial cells, NF-kB activation upregulates IL-6, granulocyte colony-stimulating factor (G-CSF), GM-CSF, macrophage inflammatory Protein 2 (MIP-2), keratinocyte-derived chemokine (KC), and RANTES

It can thus be inferred that donor inflammation does not represent a major mechanism of DCD related complications such as ischemic cholangiopathy

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[202] ApoSOD1 enters the mitochondrial intermembrane space via translocase of the outer mitochondrial membrane in the outer mitochondrial membrane, and subsequent CCSmediated metal incorporation and disulfide bond formation trap SOD1 within this compartment (Figure 6)