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They found that these culture conditions led to reversible blockage of senescence, increased proliferation, and allowed these cell lines to propagate longer in culture while still maintaining signature genetic changes of the original tumors ( BRAF V600E anaplastic PXA (JHH-PXA1) patients exhibited growth sufficient for preclinical testing in vitro

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By using the methods of system pharmacology and network pharmacology, the scientific connotation of its integrated regulation of tumor immune cycle was revealed from the perspective of multi-component-multi-target-multi-pathway

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