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The mutation analyses could be interpreted as heterozygous, homozygous or compound heterozygous without additional PCR runs since the wild type probes have been incorporated into the test kit for comparison

of course, ascertainment is difficult if the characteristic clinical dyad of hemolytic anemia and metabolic acidosis is not recognized and urine organic acid studies are not obtained

Hemolytic anemia was reported to be significantly more severe with G6PD Mediterranean and Cairo compared to G6PD A-, indicating a direct positive correlation between enzyme deficiency and severity of clinical manifestations

Zhang X, Zheng C, Gao Z, Chen H, Li K, Wang L, et al

70 Glutathione Side Effects and Risks Glutathione injections are generally considered safe, but side effects can occurespecially at higher doses