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B 12 deficiency can also result in neurological problems

GST conjugation activity GSTs have multiple biological roles, including cell protection against oxidative stress and several toxic molecules, and are involved in the synthesis and modification of leukotrienes and prostaglandins 1

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In vivo experiments using a nude mouse model confirmed the tumor-suppressive effects of JR, demonstrating reduced hypoxia and decreased expression of Wnt/-catenin signaling components

A reduction in the expression of E-cadherin and -catenin was found using transcription analysis in both intestinal biopsies of CD patients and Caco-2 cells (265)