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In PD, persistent microglial activation and the production of ROS lead to the release of pro-inflammatory cytokines, establishing a self-perpetuating cycle (Badanjak et al., 2021

Additionally, BCL2-inhibitors have been shown to have senolytic effects in some senescent cell models 1,4

Additionally, glutathiones antioxidant, anti-inflammatory and muscle reparative activities helps to recover faster post-infection.

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But when it comes to weight changes, its a bit different