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Additionally, NETs can aid in mediating liver IRI, promoting tumor progression, and most recently, in mediating early graft rejection in liver transplantation

doi: 10.3389/fpls.2014.00442 Received 24 June 2014 Accepted 18 August 2014 Published 09 September 2014 Volume 5 - 2014 Edited by Nicole Linka, Heinrich-Heine Universitt Dsseldorf, Germany Reviewed by Viktor Zarsky, Charles University, Czech Republic

P300 and SIRT1 are the regulators for H3K18la in porcine GCs P300 is currently recognized as the most extensively studied lactyltransferase, reported in humans and mice to catalyze the binding of lactyl-CoA to histone lysine residues in a lactate-dependent manner 23,28 (Fig