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PDE5 inhibitor: sildenafil Sildenafil has demonstrated therapeutic efficacy in HAPH patients

10.1016/j.ijsu.2019.07.023 16 KataokaH.YagiT.IkedoT.ImaiH.KawamuraK.YoshidaK.et al (2020)

Ferroptosis is involved in regulating the occurrence and progression of diseases such as cancer, respiratory system diseases, cardiovascular system diseases, diabetes mellitus, and urinary system diseases and plays a key role in disease treatment (11) ( Figure 1 )

Research note: A 2025 literature and patent review catalogued BPC-157's multifunctional activity across gastrointestinal, musculoskeletal, neurological, and cardiovascular preclinical models

Co-culture experiments with PC3 WT and GGT1 + cell lines were performed using 6-well (24 mm) PET inserts with 0.4 m pores (VWR, 76313-902 or Corning, 354570)