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Vasanthabharathi V, Lakshminarayanan R, Jayalakshmi S

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T.SaffitzJ

Future work will also mechanistically address how the kinetics of PDHC and OGDC inhibition and recovery under specific conditions are affected by the quantitative distribution of these lipoic adducts, and to what extent the reduction of RNS-mediated modifications and the general turnover of PDHC and OGDC contribute to their recovery

These approaches eliminate risks associated with alloimmunization and donor-derived variability while potentially simplifying regulatory classification when cells are minimally manipulated