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JAMA 2021;326:1504-15.ArticlePubMedPMC 82

Moreover, the distinction between causal and correlational interpretations is critical

Most ophthalmologists start treatment with one of the first-line therapy approved agents: a beta-blocker once daily in the morning or a prostaglandin analog once daily at night, depending on training, personal experience, and patients medical history

Here's what the research really shows

They are characterized by decreased iron storage due to ferritin downregulation and increased expression of FPN and TfR1, all features consistent with a larger LIP [60, 61]