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Recent studies have shown that synthetic monoclonal antibodies specific for SLC1A5 (i.e., KM4008, KM4012, and KM4018) are an effective therapeutic option for suppressing glutamine-dependent growth of CRC cells, but their efficacy in other cancer cells remains unclear 88

The FSP1-CoQ10-NAD(P)H pathway exists as a stand-alone parallel system, which co-operates with System X c /GSH/GPX4 axis to suppress phospholipid peroxidation and ferroptosis (Jo et al., 2022)

Targeting IRAK4 may in fact offer a potential strategy to alleviate hyperinflammatory features

YangKLiuXLiuYWangXCaoLZhangXet alDC-SIGN and toll-like receptor 4 mediate oxidized low-density lipoprotein-induced inflammatory responses in macrophages