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Wound-healing and transwell assay B16F10 and 4T1 tumor cells were cultured in 12-well plates at a density of 3 10 6 cells per well

A murine model of sepsis was established using the CLP method as described by 2.2 Drug management AB4 (HY-N0205, HNMR purity 98%, analytical grade) and FPS-ZM1 (HY-19370, LCMS purity 99.87%) were purchased from MedChemExpress (Monmouth, NJ, USA)

In healthy cells, more than 90% of glutathione stays in its active, reduced form, ready to neutralize free radicals

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Under aerobic conditions, pyruvate formed as a product of glycolysis goes through oxidative decarboxylation, a process that removes a carboxyl group as CO 2 to form acetyl coenzyme A (acetyl-CoA), the typical starting molecule of the TCA cycle [4]