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We propose CaMKK2 as a rational treatment target for bipolar disorder as it links together key facets of the condition including genetic polymorphisms/mutations, defects in signal transduction, mood stabiliser action, and metabolic dysfunction

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This pentadecapeptide demonstrates resistance to degradation in gastric juice, a property that distinguishes it from many therapeutic peptides that require modified administration routes to avoid gastric inactivation

Repeated administration of dapirolizumab pegol in a randomised phase I study is well tolerated and accompanied by improvements in several composite measures of systemic lupus erythematosus disease activity and changes in whole blood transcriptomic profiles

Alopecia is multifactorial: androgen-driven miniaturization, inflammation, microbial overgrowth, and vascular insufficiency can all contribute