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Following recommended dosages and consulting a healthcare provider before starting any new supplement regimen is important

J Neurochem 68, 22732280 (1997)

Individual reactions can vary based on personal health conditions and concurrent medications, and human long-term safety data are limited because no large clinical trials have been completed

One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition

What to consider if your results are out of range: If you're low in folate, increase your intake of naturally folate-rich foods such as spinach and other dark greens, asparagus, Brussels sprouts, avocado, black-eyed peas and other legumes, and citrus fruits