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However, PAI-1 carbonylation has been demonstrated to influence its functional activity and structural stability [38], therefore carbonylated PAI-1 may exhibit reduced activity, and we hypothesize that it could trigger a compensatory mechanism leading to an increase in its overall concentration observed in our cohort

Combining RPLC and HILIC techniques followed by mass spectrometric analysis can significantly enhance the identification of metabolites

10.1016/0168-8278(92)90152-f 47 LiB

Pressure buildup in the lower leg veins causes blood to leak into the skin

(2012) vitamin B(12) deficiency in infants secondary to maternal causes