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For instance, LXR, a nuclear receptor for oxysterols, represses the expression of CYP51A1 and farnesyl-diphosphate farnesyltransferase 1 (FDFT1) in human HepG2 and HEK293 cells by binding to negative LXR response elements (nLXREs) in their promoters [39]

Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimers disease and Parkinsons disease: a large-scale multi-trait association analysis

sativa hydro-alcoholic extract prevents scopolamine-induced spatial memory deficits, decreases anticholinesterase activity in brain tissue, and reduces oxidative stress