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Excess B12 does not generally cause direct harm to the kidneys or liver in people with healthy organs

Multiple Sclerosis: Multiple sclerosis is an autoimmune disease where the immune system attacks the myelin sheath that encases the nerves

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In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy [see Clinical Pharmacology (12.3)]

Since vitamin B12 is still necessary for bodily health, deficiency in this key vitamin can lead to a number of negative symptoms, including: However, since vitamin B12 is necessary for so many vital things, symptoms can vary from individual to individual