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This is because their suppression is likely to inhibit generic cell death mechanisms rather than specifically counteracting copper toxicity in ATP7B-KO cells

Although the specific mechanisms affecting OTUD1 expression remain to be further investigated, existing studies suggest that OTUD1 may be an important factor influencing the prognosis and drug resistance of ccRCC patients[104]

(2023, August 21)

Compared to the ICH group, the crocin-treated group significantly increased the activities of SOD and GSH-px ( 2+ concentration and the upregulation of GPX4, FTH1, and SLC7A11 genes demonstrated the inhibition of ferroptosis in neuron cells by crocin ( 6 Clinical translation discussion Compared with the previous review published by Zhou et al., we have summarized the mechanism of ferroptosis in stroke and summarized its natural products, rather than only focusing on ischemic stroke (Zhou et al., 2024b)

Yes, if your institution is VAT-registered (has a Umsatzsteuer-Identifikationsnummer)