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Furthermore, it has been reported that excessive production of NEFA and BHB may compromise immunity, resulting in abnormal regulation of immune and inflammation responses (83)

161 Although many traditional formulations are supported by in vitro and in vivo studies, 162 the precise pharmacological effects of individual herbs on inner ear physiology are often incompletely characterized

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A schematic representation of the workflow is presented in Fig 1, and this studys implications with respect to drug repurposing are discussed