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In contrast, normal and healthy cells metabolize glucose via glycolysis into pyruvate, which is then sent to the tricarboxylic acid cycle (TAC) to generate a large amount of ATP molecules via oxidative phosphorylation (134)

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Additionally, in rd10 mice, the levels of iron metabolism-related proteins, including TF, TFR, ferritin (Ft), and ceruloplasmin (Cp), were also elevated

Specifically, in AGA patients, 30-50 hair follicles were harvested from both the frontal balding area (AGA-F) and occipital non-balding area (AGA-O), respectively, while in healthy male controls, 30-50 hair follicles were collected from the frontal non-balding area (Normal-F)

Simply through switching on and off the systemic iron regulator, the enteroid model provides a powerful tool to study iron uptake and efflux, as well as intracellular iron trafficking through intestinal epithelial cells