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intermedius -derived bacterial pore-forming toxins can trigger necroptosis of erythrocytes, which is suggested as a bacterial strategy to promote their growth [198]

Treatment with dichloroacetate, an inhibitor of pyruvate dehydrogenase kinase, increases pyruvate dehydrogenase activity and systolic blood pressure in 34 weeks old SHR and WKY rats 55

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Samples were then mixed with nitric acid 65% and heated at 80 C overnight in the same glass vials closed with a lid carrying a Teflon septum