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Podocytes, a cell type playing a major role in glomerular filtration barrier integrity, has been shown to display ferroptosis activation upon high glucose exposure through the antioxidant molecule peroxiredoxin 6 (Prdx6) (65)

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Studies to definitively establish if this is true are not only needed, but also, they are readily justifiable on the following basis: there are well-grounded theoretical benefits, and, although generally safe, there are also potential risks

coli fluorescence microscopy 110 8 cells per condition were collected and treated as previously described for flow cytometry

The most successful strategy toward obtaining GSH overproducing strains was classical selection which resulted in GSH contents of 35 % [14]