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For short-chain peptides, mucosal absorption can be meaningful

Malik TA (2015) Inflammatory bowel disease: historical perspective, epidemiology, and risk factors

doi: 10.1155/2022/4081380 44 ChenTCChuangJYKoCYKaoTJYangPYYuCHet al

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DD-H/P NCs could provide PKM2 silencing efficiency of 75%, significantly reduce intracellular ATP levels by 60%, inhibit ABC transporter-mediated DOX efflux, and enhance DOX accumulation in drug-resistant tumor cells