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2 Both native highlanders and newcomers are at risk of high-altitude disease

Thus, depending on the stimulus applied to the cells, hGH may either trigger (Jeay et al, 2000), inhibit (as we have reported in human monocytes exposed to lipopolysaccharides (Haeffner et al, 1997) or decrease (as in the present study) translocation of NF- B into cell nuclei

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Because of its defined molecular profile, the compound blend is frequently used in laboratory studies examining peptide signalling and regulatory processes

Data availability The NGS sequencing data supporting the findings of this study have been deposited in the SRA database with accession numbers PRJNA1119646 and PRJNA1119922