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Iron overload appears to be associated with an increased risk of cancer, particularly HCC, but also colorectal, breast, and prostate cancers ( TP53 ) and are being studied for their prognostic role and as potential therapeutic targets (355357)

A third factor which may contribute to protein polymorphism is post-translational modification

Myeloid-derived suppressor cells (MDSCs) and activated tumor-associated macrophages express ARG1, which consumes arginine to form a microenvironment that is not conducive to T cells, resulting in tumor immunosuppression (Rodriguez et al., 2017

Deep learning approaches trained on large datasets of confirmed endometriosis cases show performance comparable to expert radiologists