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The currently established minimal effective dose of HMB is 1.5 g per day, with 3 g per day offering additional benefits on lean body mass, while 6 g per day do not provide any additional gains in lean mass beyond what was reported with a 3 g dose [169]

3.3 Liver lipid metabolism-related enzymes activity Figure 2 shows the activity of the oxidative enzyme CPT-1 (Figure 2A) and the lipogenic enzymes FAS (Figure 2B), ACC (Figure 2C), G6PDH (Figure 2D), and EM (Figure 2E)

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These resultant molecules can then be repurposed and funneled into various bioenergetic and biosynthetic pathways, which is especially crucial during states of cell stress or nutrient paucity [11, 12]