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Stroke, particularly ischemic stroke, is a leading cause of adult disability and death worldwide, characterized by the sudden interruption of cerebral blood flow and the subsequent cascade of energy failure, excitotoxicity, oxidative stress, and neuronal death [8487]

10.1038/ncomms11312 104 Keren-ShaulH.SpinradA.WeinerA.Matcovitch-NatanO.Dvir-SzternfeldR.UllandT

The high failure rates of experimental drugs in late-stage clinical trials highlight a disconnect between preclinical findings and human studies, largely due to inadequate disease models that fail to capture the full complexity of human AD pathology ( in vitro and in vivo studies showing their efficacy in reducing oxidative stress, neuroinflammation, and A accumulation (Mohamed Yusof and Mohd Fauzi 2024)

Phosphatidylcholine (PC) is the most essential phospholipid and its found in young, healthy cellular membranes

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