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You have two main options, Peter Lurie, a former F.D.A

10.1007/s43032-020-00439-5 50 LapuenteM.EstruchR.ShahbazM.CasasR

Both Shh and IGF-1 enhanced Akt and MAPK phosphorylation and myogenic factor expression levels in C2 myoblasts in a dose-responsive manner, having additive effects