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Ototoxicity and irreversible hearing impairment In addition to peripheral neuropathy, long-term platinum accumulation in cochlear tissues is the core driver of delayed, irreversible post-chemotherapy ototoxicity

CRF activation in the amygdala has also been found to be involved in reinstatement of methamphetamine seeking in response to stress in animal models [49]

The deposition of GAG was detected by alcian blue staining

The peptide's interaction with growth factor signalling pathways and its influence on wound healing cascades continue to be active areas of investigation in preclinical studies