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pTEF1 was chosen for bypassing GSH-regulated GSH1 expression as pTEF1 is a relatively strong promoter, commonly used in yeast expression systems

The responses to needles of different thicknesses designed, specifically for the pain test, were determined from the animals retraction of the hind paw

Furthermore, enhanced reactive oxygen species (ROS) production after aminoglycoside treatment has been shown to promote apoptotic hair cell death via caspase-3 and nuclear factor kappa (NF-B) activation (Lee et al

While free radicals are a natural part of the bodys functioning, an overabundance can lead to oxidative stress, resulting in cellular damage and contributing to various chronic diseases (Zakeri et al., 2021)