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Triple-negative breast cancer (~ 15% of all breast cancers) lacks expression of ER, PR, and HER2, making targeted therapies ineffective and resulting in worse survival rates compared to other subtypes [3,4,5]

Also, the finding that a CD8-specific T-cell response can be elicited in neoepitopes derived from Histidine Ammonia-Lyase (HAL), Neuraminidase 2 (NEU2), Proprotein Convertase Subtilisin (PCSK9), Programmed Cell Death 10 (PDCD10), Supervillin (SVIL) and tRNA Splicing Endonuclease Subunit 54 (TSEN54) variants is in line with the notion that specific T cell-mediated immunotherapy can be applied for MB (189)

While there may be some promising preliminary findings overall, this research is still new and caution should be taken when concluding that taking oral supplements of GSH daily is necessary or beneficial

Robakis D, Fahn S (2015) Defining the role of the monoamine oxidase-B inhibitors for Parkinsons disease

Nature 633 , 442450 (2024)