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[DOI] [PMC free article] [PubMed] [Google Scholar] Ueno S

Discussion APR-246 was identified in the monumental effort to create a pan-acting mutant p53 rescuing drug

The AD169 attenuated strain was quickly abandoned whereas the Towne attenuated strain progressed to extensive testing in recipients of solid organ transplants and healthy volunteers 276

Proper documentation supports consistent use and tracking of the peptide, reducing the risk of errors in experiments

One such protein with conserved cysteines is the gap junction protein, connexin 43 (Cx43), belonging to the connexin family, and is the most commonly expressed member in different cell types