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If these symptoms worsen and, patient develops life-threatening reactions such as anaphylaxis, Stevens-Johnson syndrome and epidermal necrosis, emergency treatment is required

Numerous natural polyphenols have been identified as NRF2 activators

(2025) 21:e1013124

10.1371/journal.pgen.1000836 PLoS Genet

This modulation effectively restored stromal homeostasis, as evidenced by the enhanced drug permeability in a desmoplastic PDAC xenograft tumor model, detailed in Fig